Getting My ceesdekker.net To Work
Getting My ceesdekker.net To Work
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Employing solitary-molecule optical and AFM imaging and force-spectroscopy techniques, we seek to unravel the mechanistic aspects of the construction and dynamics of chromosomes. Our study pursuits consist of:
But how do morality, the dignity from the individual, my practical experience in the meaning of everyday living, comply with from your movement of atoms? A purely naturalistic standpoint fails listed here; a Christian perspective, I do think, is a much more reasonable technique to interpret these elements of truth.’
Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins
Our perform was speedily adopted up by Other folks, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors comprised of one- and multi-walled carbon nanotubes in Used Physics Letters.
This yielded a breakthrough. Inside of just a few months, we were being able to measure transport by an individual single-walled carbon nanotube. Determined by very low-temperature experiments by a superb PhD student in my group, Sander Tans (now a valued colleague and professor at Delft University of Engineering by having an Lively investigate lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were genuine quantum wires with extremely extended (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic structures to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this evaluate the elemental purpose of spatial confinement within the molecular and cellular stage. Our initiatives include things like the next:
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in pink, ceesdekker.net along with a 3D rendering of your motion with the DNA rod is displayed.
Imagine if, instead of employing common leading-down silicon electronics, transistors may very well be built from the bottom up utilizing one natural and organic molecules as the switching factors? This concept, which turned the basis of right now’s discipline of molecular electronics, to start with emerged in the 1970s.
But carbon nanotubes have remained a research matter of significant interest to lots of. In fact, the outlook on making use of carbon nanotubes to build realistic units, in parts for example radio-frequency electronics, electronic electronics and versatile electronics, remains dazzling.
Testing pseudotopological and nontopological types for SMC-driven DNA loop extrusion in opposition to roadblock-traversal experiments
Mother nature Physics thanks the nameless reviewers for his or her contribution for the peer evaluate of this do the job.
As an example, we look at the nucleopore sophisticated, a gateway involving the cell nucleus and the cytoplasm. This is a really challenging process and as a consequence challenging to examine inside a cell, so we use biomimetics. We reconstruct holes after which you can insert specific factors of the nucleopore advanced to review transportation by way of it at the single-molecule stage.’
‘I am driven by speculate and questions. On a material degree I uncover responses in physics, but I working experience my deepest happiness with God. That faith also drives my science And the way I handle persons.